Best Flea And Tick Drops For Dogs in 2022 [*Top Picks*]

Looking for the best flea and tick drops for dogs on the market? We’ve got you covered. Check out our ratings of absolute bestsellers below and make a final decision.

4711 Reviews Scanned

  • PETARMOR Plus for Dogs Flea and Tick Prevention for Dogs, Long-Lasting & Fast-Acting Topical Dog Flea Treatment, 3 Count, PetArmor Plus Flea & Tick Prevention for Large Dogs with Fipronil (45 to 88 Pounds), 3 Monthly Treatments
    Bestseller #1
    PETARMOR Plus for Dogs Flea and Tick Prevention for Dogs, Long-Lasting & Fast-Acting Topical Dog Flea Treatment, 3 Count, PetArmor Plus Flea & Tick Prevention for Large Dogs with Fipronil (45 to 88 Pounds), 3 Monthly Treatments (386)
      EFFECTIVE, WATERPROOF FLEA TREATMENT FOR DOGS: PetArmor Plus is a waterproof, flea & tick topical prevention for dogs that kills fleas, flea eggs, flea larvae, ticks, and chewing lice for up to 30 days after application. TRUSTED, VET QUALITY FORMULA: Containing fipronil and (S)-methoprene, the same active ingredients as FRONTLINE Plus for Dogs. PetArmor Plus for Dogs has a powerful formula that starts to kill fleas within 24 hours. BREAK THE FLEA CYCLE: Unlike other flea and tick treatments that may temporarily suppress flea activity, PETARMOR Plus Dog Flea Treatment works by effectively breaking the flea life cycle. Kill flea eggs and larvae to prevent re-infestation. FAST ACTNG LONG-LASTING FLEA AND TICK PROTECTION: One application of PetArmor Plus lasts up to 30 days nose to tail. A 6-dose package lasts up to six months. EASY-TO-USE, LONG-LASTING: PetArmor Plus flea and tick treatment comes with three (3) waterproof topical applications that provides your pet flea protection and control for three (3) months.
  • K9 Advantix II Flea and Tick Prevention for Extra-Large Dogs 1-Pack 4 Monthly Doses, Over 55 Pounds
    Bestseller #1
    K9 Advantix II Flea and Tick Prevention for Extra-Large Dogs 1-Pack 4 Monthly Doses, Over 55 Pounds (386)
      4 monthly applications of K9 Advantix II flea and tick prevention for extra-large dogs weighing 55 pounds or more K9 Advantix II flea and tick prevention for dogs works through contact, so fleas, ticks and mosquitoes do not have to bite your dog to die K9 Advantix II flea and tick control for dogs is an easy to apply topical formula Starts working to kill fleas within 12 hours and keeps working for 30 days Suitable for effective year-round dog flea and tick treatment for extra-large dogs
  • Hartz UltraGuard Dual Action Flea & Tick Topical Dog Treatment and Flea and Tick Prevention, 6 Months, 15-30 Pound Dogs
    Bestseller #1
    Hartz UltraGuard Dual Action Flea & Tick Topical Dog Treatment and Flea and Tick Prevention, 6 Months, 15-30 Pound Dogs (386)
      KILLS FLEAS & TICKS: Kills fleas, flea eggs, deer ticks, and brown dog ticks on contact – it is important for your pup to have a flea and tick prevention treatment all year round! PREVENTS RE-INFESTATION: This topical formula prevents re-infestation by breaking the flea life cycle for up to 30 days. FAST ACTING FULL BODY PROTECTION: Active ingredients spread across the skin using your dog’s natural oil to quickly travel across the coat for full body protection from head to tail. 6 MONTHLY FLEA & TICK TREATMENTS: Contains 6 single dose tubes (1 tube per monthly application) for non-stop protection for up to 6 months. Apply at the base of your dog’s back between the shoulder blades each month.
  • K9 Advantix II Flea and Tick Prevention for Large Dogs 4-Pack, 21-55 Pounds
    Bestseller #1
    K9 Advantix II Flea and Tick Prevention for Large Dogs 4-Pack, 21-55 Pounds (386)
      4 monthly applications of K9 Advantix II flea and tick prevention for large dogs weighing 21-55 pounds K9 Advantix II flea and tick prevention for dogs works through contact, so fleas, ticks and mosquitoes do not have to bite your dog to die K9 Advantix II flea and tick control for dogs is an easy to apply topical formula Starts working to kill fleas within 12 hours and keeps working for 30 days Suitable for effective year-round dog flea and tick treatment for large dogs
  • Amazon Brand - Solimo for Dogs Large Dog (45-88 pounds) Flea and Tick Treatment, 3 Doses
    Bestseller #1
    Amazon Brand - Solimo for Dogs Large Dog (45-88 pounds) Flea and Tick Treatment, 3 Doses (386)
      Solimo Flea & Tick Topical starts eliminating fleas and ticks within 24 hours of treatment. Two active ingredients combine power to prevent flea infestations by killing flea eggs and flea larvae. One application provides up to 30 days of protection: Solimo Flea & Tick Topical kills fleas, ticks, mosquitoes, biting flies and chewing lice. 24 hours after application, your pet's treatment is protected against rain, puddles and even after bathing. Satisfaction Guarantee: We’re proud of our products. If you aren’t satisfied, we’ll refund you for any reason within a year of purchase. 1-877-485-0385 An Amazon Brand
  • Hartz UltraGuard Dual Action Topical Flea & Tick Treatment for Dogs and Puppies - 31-60lbs, 3 Monthly Treatments
    Bestseller #1
    Hartz UltraGuard Dual Action Topical Flea & Tick Treatment for Dogs and Puppies - 31-60lbs, 3 Monthly Treatments (386)
      Fast-acting topical drop formula kills fleas, flea eggs, deer and brown dog ticks, plus prevents re-infestation for 30 days Includes 3 monthly treatments in easy to apply, single dose tubes This product also kills deer ticks, which may carry Lyme disease For use on dogs and puppies 12 weeks or older that weigh 31-60 pounds Apply at the base of the pet's back between the shoulder blades
  • Frontline Plus Flea and Tick Treatment for Dogs (Small Dog, 5-22 Pounds, 3 Doses)
    Bestseller #1
    Frontline Plus Flea and Tick Treatment for Dogs (Small Dog, 5-22 Pounds, 3 Doses) (386)
      Waterproof flea and tick treatment for dogs: Frontline Plus for Dogs provides waterproof, fast-acting, long-lasting flea and tick treatment and control for your dog. This product is approved for use on dogs 5-22 lbs. Break the flea life cycle with frontline: Frontline flea and tick treatment for dogs kills adult fleas plus flea eggs and larvae to stop existing infestations and prevent establishment of new infestations. Kills fleas and ticks: Frontline flea and tick treatment for dogs kills fleas, flea eggs, lice, and ticks. This flea and tick treatment kills ticks, including those that may transmit Lyme disease. Trusted flea and tick protection for dogs: Frontline has been trusted by veterinarians for nearly 20 years. Made with 2 tough killing ingredients, fipronil and (S)-methoprene – one to kill adult fleas and ticks and the second to kill flea eggs and larvae – this fast-acting, long-lasting protection provides flea and tick control for dogs and puppies 8 weeks and older Lasting flea and tick protection: Frontline's long-lasting formula isstored in the oil glands of the pet’s skin to give non-stop flea and tick protection for a full 30 days. Frontline flea and tick treatment for dogs works non-stop for a full 30 days. A 3-dose supply lasts for 3 months.
  • Vet's Best Flea and Tick Spot-on Drops | Topical Flea Treatment Drops for Dogs |Plant-Based Formula | 4 Month Supply for Large Dogs
    Bestseller #1
    Vet's Best Flea and Tick Spot-on Drops | Topical Flea Treatment Drops for Dogs |Plant-Based Formula | 4 Month Supply for Large Dogs (386)
      SAFE & EFFECTIVE: Kills and repels fleas and ticks by contact for up to one month for large dogs over 40 lbs and 12 weeks or older. EASY APPLICATION: Simply use the supplied dropper applicator and squeeze the specified amount betweeh the shoulder blades and base of the tail. NATURAL FORMULA: Made with a unique blend of certified natural oils like Clove, Thyme and Cinnamon oils. SAFE TO USE FOR DOGS: Formulated for dogs and puppies 12 weeks or older when used as directed. MADE IN THE USA: Our products are proudly manufactured in the USA with quality domestic and internationally sourced ingredients.
  • K9 Advantix II Flea and Tick Prevention for Large Dogs 2-Pack, 21-55 Pounds
    Bestseller #1
    K9 Advantix II Flea and Tick Prevention for Large Dogs 2-Pack, 21-55 Pounds (386)
      2 monthly applications of K9 Advantix II flea and tick prevention for large dogs weighing 21-55 pounds K9 Advantix II flea and tick prevention for dogs works through contact, so fleas, ticks and mosquitoes do not have to bite your dog to die K9 Advantix II flea and tick control for dogs is an easy to apply topical formula Starts working to kill fleas within 12 hours and keeps working for 30 days Suitable for effective year-round dog flea and tick treatment for large dogs
  • Frontline Plus Flea and Tick Treatment for Dogs (Large Dog, 45-88 Pounds, 3 Doses)
    Bestseller #1
    Frontline Plus Flea and Tick Treatment for Dogs (Large Dog, 45-88 Pounds, 3 Doses) (386)
      The #1 name in flea & tick protection trusted by pet owners for over 20 years, this waterproof, fast-acting flea and tick treatment kills fleas, flea eggs, lice, and ticks, including those that may transmit Lyme disease. Designed for use only with dogs and puppies, this long-lasting treatment is made for dogs eight weeks or older. Made with two active ingredients, fipronil and (S)-methoprene, this treatment stops infestations and prevents new ones. Applied on a single point on your pet, the treatment rapidly covers your dog's entire body and deposits in the sebaceous glands. These glands as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. One dose of FRONTLINE Plus lasts 30 days.
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